Ka holomua o ka noiʻi ma ka synthesis enzymatic o nā precursors hiki o Clenbuterol ma ka laulima ʻana ma waena o ke Kulanui ʻEpekema a me ka ʻenehana Norewai a me Shangke Biomedical

ʻO Clenbuterol, he agonist β2-adrenergic (β2-adrenergic agonist), e like me ka ephedrine (Ephedrine), hoʻohana pinepine ʻia i ka lāʻau lapaʻau e mālama i ka maʻi pulmonary obstructive mau loa (COPD), Hoʻohana ʻia hoʻi ia ma ke ʻano he bronchodilator e hōʻoluʻolu i nā exacerbations koʻikoʻi o ka hānō. I ka hoʻomaka ʻana o nā makahiki 1980, ua ʻike hewa ka hui ʻAmelika ʻo Cyanamid he mau hopena maopopo ia o ka hoʻoulu ʻana i ka ulu ʻana, ka hoʻomaikaʻi ʻana i ka nui o ka ʻiʻo lean a me ka hōʻemi ʻana i ka momona, no laila ua hoʻohana ʻia ia ma ke ʻano he clenbuterol i ka mahi holoholona. Eia naʻe, ma muli o kona mau hopena ʻaoʻao, ua pāpā ke Kaiāulu ʻEulopa i ka hoʻohana ʻana o clenbuterol ma ke ʻano he mea hoʻohui hānai mai Ianuali 1, 1988. Ua pāpā ʻia e ka FDA i ka makahiki 1991. I ka makahiki 1997, ua pāpā loa ke Kuhina Mahiʻai o ka Repubalika o Kina i ka hoʻohana ʻana i nā hormones beta-adrenergic i ka hana hānai a me ka mahi holoholona, ​​a ua helu mua ʻo Clenbuterol hydrochloride.

Eia nō naʻe, ua hōʻike ʻia nei ka racemic Clenbuterol e hōʻemi i ka pilikia o ka maʻi Parkinson. No ka hōʻoia ʻana i nā isomers (a i ʻole nā ​​​​​​mea ʻelua) e hana i kēia hopena, pono e aʻo ʻia ka enantiomer Clenbuterol maʻemaʻe ma ke kaʻawale.