Ua hala ka mea maka NMN o Syncozymes i ka "Acute Oral Toxicity Test"

ʻO ka hoʻomaka ʻana o ke kumumanaʻo o ka "lāʻau lōʻihi" NMN ua hoʻoulu i nā haʻalulu i ka mākeke kapikala. I ka waena o Iulai, ua lilo ka waihona manaʻo NMN "Internet celebrity longevity medicine" i lio ʻeleʻele i ka mākeke. Ua pani ʻia nā waihona o nā hui pili i kekahi ma hope o kekahi, a ua loaʻa i kahi hui i helu ʻia he 8 mau palena i kēlā me kēia lā i 11 mau lā.

ʻO ka inoa piha o NMN ʻo nicotinamide mononucleotide, ʻo ka inoa Pelekane ʻo Nicotinamide Mononucleotide, ʻo ia ka mea mua o NAD+ a hiki ke hoʻololi ʻia i NAD+ i loko o ke kino. Komo ʻo NAD i nā hopena biochemical ma mua o 500 i loko o ke kino kanaka, e hāʻawi ana i ka ikehu a me ke ola i nā cell kanaka. Ua hōʻike nā haʻawina hoʻokolohua holoholona a me nā mea ʻē aʻe e pili ana e hiki i ka hoʻohui ʻana o NMN i nā poʻe waena a me ka poʻe ʻelemakule ke hoʻopaneʻe i ka ʻelemakule kanaka.

I ka makahiki 2019, ua ʻoi aku ka mākeke anti-kahiko honua ma mua o 190 biliona kālā ʻAmelika. Ma ke ʻano he ʻano huahana mālama ola kino anti-kahiko hou, ua huki ʻo NMN i ka manaʻo nui no kona palekana a me ka pono.

ʻO Shangke Bio kekahi o nā mea hoʻolako mua o ka honua no nā mea maka NMN. Mai ka makahiki 2009, ua noiʻi ʻo Shangke Bio i ka hoʻomohala ʻana a me ka hana ʻoihana o nā huahana ʻohana NAD, me ka hoʻomohala ʻana a me ka hana ʻana o NMN, NAD, NADH, NADP a me nā huahana ʻē aʻe. ʻO Shangke Bio ka hui mua ma Kina e hoʻokō i ka kūloko o nā huahana NAD.

I Iulai 2020, ua hala ka mea maka NMN a Shangke Bio i ka "hoʻāʻo ʻawaʻawa waha koʻikoʻi" o ka hui mana, nāna i hōʻoia hou aku he palekana ka mea a ʻaʻohe mea ʻawaʻawa.