Ua komo ʻo Shangke Bio a me Zhejiang Supor Pharmaceutical Co., Ltd. i ka 2020 Nanjing API CHINA API Exhibition a hana i kahi hōʻike hoʻonaʻauao kūikawā ma NMN.

Ua hāʻawi ʻo Kauka Zhu i kahi haʻiʻōlelo mai ka hoʻomohala ʻana o NMN, a wehe mālie i ka mea huna o ka lāʻau anti-kahiko NMN: NMN i hoʻopau ʻia ʻo β-nicotinamide mononucleotide, ʻo ia ka precursor o NAD +;ʻO nā hopena hoʻokolohua kūpono i paʻi ʻia i loko o kahi pūʻulu o nā puke moʻolelo ʻepekema honua kiʻekiʻe e hōʻike ana, manaʻoʻiʻo ʻo ka ʻike o ka NAD + i loko o ke kino o ke kanaka e emi ana me ka makahiki, e alakaʻi ana i ka ʻelemakule mai ka makahiki o 30, me nā wrinkles, hoʻomaha hoʻomaha ʻiʻo, hōʻiliʻili momona, a hoʻonui i ka pilikia. ʻo ka maʻi puʻuwai, ke koko kiʻekiʻe, ka hahau ʻana, ka maʻi diabetes, a me ka maʻi Alzheimer.Ua ʻike ʻia ka haʻawina i ka wā e haʻahaʻa ai nā cell i NAD +, pane lākou ma ka hōʻike ʻana i ka mea lawe SLC12A8, e ʻae ana i ka absorption maikaʻi o NMN mai ke kahe koko, ʻoiai ʻo ka SLC12A8 transporter gene i ʻike ʻia e hōʻike ʻia i loko o nā ʻiʻo he nui a ma ka ʻōpū. kiʻekiʻe loa ka ʻāpana.I loko o ka ʻōpū, hoʻopili koke ʻia ka NMN mai ka ʻōpū liʻiliʻi i loko o 2-3 mau minuke a hoʻololi ʻia i NAD + i loko o 10-30 mau minuke.

Ua hōʻoia ʻia a kākoʻo ʻia ka hopena anti-aging o NMN e ka hapa nui o nā hihia maoli.I kēia manawa, ua lilo ʻo Iapana i ʻāina i ʻae i ke kānāwai i ka NMN ma ke ʻano he meaʻai meaʻai.

I Ianuali 2019, he 188 wale nō nā huahana o NMN ma ka pūnaewele holoʻokoʻa, a ma ka hopena o ʻAukake 2020, ua ʻoi aku ka nui o nā huahana ma ka pūnaewele puni honua holoʻokoʻa ma mua o 2,962.Aia ka nui o nā huahana, nele i nā kūlana ʻoihana, a me ka noʻonoʻo ʻole no ka palekana a me ka pono.Eia kekahi, ʻaʻohe ʻenehana NMN he nui, a hui pū ʻia nā huahana.

ʻO ka mākeke huahana anti-aging honua (me ʻekolu mau ʻāpana o nā huahana mālama cosmetic, meaʻai a me nā huahana anti-aging pharmaceutical) i waiwai ʻia ma US $ 250 biliona ma 2016 a manaʻo ʻia e ulu ma kahi CAGR o 5.8% a hiki i ka US $ 331.41 biliona e 2021. ʻO ʻAmelika ʻĀkau i kēia manawa ke alakaʻi nui i ka mākeke anti-aging honua, a ukali ʻia e ʻEulopa a me Iapana, a ʻo Asia Pacific ka mea i manaʻo ʻia ʻo ia ka wikiwiki e ulu nei i ka honua i ka wā e hiki mai ana.I kēia manawa, ʻoi aku ka nui o nā mea hoʻolako kumu honua o NMN ma Kina, a ʻo nā kaʻina hana e pili ana i ka synthesis chemical, chemical-enzymatic synthesis a me ke ʻano holoʻokoʻa-enzymatic.ʻO ka noiʻi lapaʻau kūpono e pili ana i nā hana kūpono o NMN ke kumu no ka ulu ʻana o ka mākeke e hiki mai ana, a ʻo ka hoʻokō kānāwai a me ka localization nā kumu nui no ka hoʻomohala ʻana i ka mākeke e hiki mai ana.He kuleana koʻikoʻi ka Coenzyme i ke kaʻina hana o ka metabolism physiological kanaka, a ua hoʻohana nui ʻia kāna mau huahana i ka ʻoihana meaʻai a me nā huahana olakino.Eia kekahi, ʻo coenzyme ke kumu kumu o nā biopharmaceuticals ʻōmaʻomaʻo.

He ʻoihana ʻo Shangke Bio e ʻike i ka hana ʻana o ka coenzyme NMN/NAD/NADH/NADP/NADPH a me nā huahana ʻē aʻe ma o ka ʻenehana catalysis enzyme holoʻokoʻa, a ua hala i ka ISO9001 quality management system certification, SELF GRAS (ka US FDA loiloi. ʻO ka helu palekana o nā meaʻai meaʻai) Ua lanakila ka palapala hōʻoia palekana a me ka "acute oral toxicity test" i kahi inoa maikaʻi ma ka ʻoihana, a lawe ʻia nā huahana i ka honua.