ʻO ka β-Nicotinamide adenine dinucleotide phosphate hydrate (NADP)
ʻO SyncoZymes (Shanghai) Co., Ltd. ka mea hana a me ka mea hoʻolako nui o β-Nicotinamide adenine dinucleotide phosphate hydrate (CAS:53-59-8) me ke ʻano kiʻekiʻe. Hiki iā mākou ke hāʻawi iā COA, ka lawe ʻana ma ka honua holoʻokoʻa, nā liʻiliʻi a me nā nui i loaʻa. Inā makemake ʻoe i kēia huahana, e ʻoluʻolu e hoʻouna mai i ka ʻike kikoʻī e pili ana i ka helu CAS, ka inoa huahana, ka nui iā mākou. E ʻoluʻolu e kelepona mai:lchen@syncozymes.com
| Inoa Kemika | β-Nicotinamide adenine dinucleotide phosphate hydrate |
| Nā huaʻōlelo like | β-Nicotinamide adenine dinucleotide phosphate hydrate |
| Helu CAS | 53-59-8 |
| Kaumaha Molekala | 743.41 |
| Formula Molekala | C21H28N7O17P3 |
| Helu EINECS. | 200-178-1 |
| mahana mālama | E mālama i kahi pouli, ka lewa inert, E mālama i loko o ka pahu hau, ma lalo o -20°C |
| ka hiki ke hoʻoheheʻe ʻia | H2O: 50 mg/mL, moakāka, melemele iki |
| pka | pKa1 3.9; pKa2 6.1 (ma 25 ℃) |
| λmax | 260nm (mālamalama ʻia) |
| Merck | 14,6348 |
| ʻŌnaehana Hoʻopaʻa Inoa Mea EPA | ʻAdenosine 5'-(trihydrogen diphosphate), 2'-(dihydrogen phosphate), P'.fwdarw.5'-ester me 3-(aminocarbonyl)-1-.beta.-D-ribofuranosylpyridinium, paʻakai o loko (53-59-8) |
| Mea Hoʻāʻo | Nā kikoʻī |
| helehelena | Pauka keʻokeʻo a melemele |
| Ka hiki ke hoʻoheheʻe ʻia | 200mg/ml i loko o ka wai |
| ka waiwai pH (100mg/ml) | 5.0～7.0 |
| Ka Nānā ʻana i ka UV Spectral ε ma 260 nm a me ka pH 7.5 | (18±1.0)×10³L/mol/cm |
| ʻIke (ma o ka nānā ʻana i ka enzymatic me G6(PDH ma ka pH 7.5, me ka hoʻohana ʻana i ka spectrophotometer, abs.340nm, ma ke kumu anhydrous) | ≥90.0% |
| Maʻemaʻe (e HPLC, % wahi) | ≥95.0% |
| Ka nui o ka wai (na KF) | ≤5% |
Pūʻolo:ʻŌmole, ʻeke pepa alumini, 25kg/Papa Kālā, a i ʻole e like me ke koi a ka mea kūʻai aku.
Kūlana Mālama:E mālama paʻa i kahi pani pouli, no ka mālama lōʻihi e mālama i ka 2~8℃.
He coenzyme ka NADP, ʻo ia kahi mea i hoʻopaʻa ʻia ai ka nicotinamide adenine dinucleotide a me kahi molekole phosphate e kahi pilina ester, a aia ma nā wahi he nui.i loko o ke ao olaola. ʻO kona mau waiwai kemika, ka spectrum absorption, ke ʻano redox, a me nā mea ʻē aʻe ua like ia me NAD (Coenzyme I). Hiki ke hoʻohana nui ʻia ʻo NADP i nā hopenai hoʻoulu ʻia e nā ʻano dehydrogenases waiʻona like ʻole, ketoreductases a me nā oxidoreductases ʻē aʻe. E like me: hiki ke hoʻemi ʻia i NADPH e nā dehydrogenases he nui e like mee like me 6-phosphoglucose dehydrogenase (EC.1.1.1.49), 6-phosphogluconate dehydrogenase (EC.1.1.1.44). Eia naʻe, ʻaʻole hiki iā ia ke hana me nā mea he nuinā dehydrogenases e hoʻohana ana iā NAD, ʻaʻole hiki ke hoʻomake pololei ʻia e ke kaulahao hanu. ʻAʻole e like me NAD, aia nui ia ma kahi kūlana i hoʻemi ʻia i loko o nā pūnaewele o nā meaola aerobic.
Wahi a ka hoʻohana ʻana o ka huahana, hiki ke puʻunaue ʻia i nā māka penei: māka biotransformation, māka reagent diagnostic, māka meaʻai olakino.
Papa Biotransformation: Hiki ke hoʻohana ʻia no ka synthesis o nā mea waena lāʻau lapaʻau a me nā API, ʻo ia hoʻi me nā enzymes catalytic, e like me ketoreductase (KRED),P450 monooxygenase (CYP), formate dehydrogenase (FDH), glucose dehydrogenase (GDH), a pēlā aku. E kali.
Papa reagent diagnostic: Me nā ʻano enzyme diagnostic like ʻole, e like me ka mea maka o nā pahu diagnostic.
Papa meaʻai olakino: ʻO ka hoʻopili ʻana o ka NADP i nā mea hoʻohui meaʻai ma ke kaʻina hana noiʻi a me ka hoʻomohala ʻana.
