β-Nicotinamide Mononucleotide (NMN)
I kēia mau lā aku nei, aia kahi nūhou maikaʻi ma ke kahua o NMN - ma hope o ka loiloi koʻikoʻi ʻana e ke kōmike ʻoihana o ka hui mana o ka US Food and Drug Administration (FDA), ua ʻāpono ʻia nā mea maka NMN o Shangke Biopharmaceutical (Shanghai) Co., Ltd. (i kapa ʻia ma hope aku ʻo "Shangke Bio") e ka ʻae ʻana o ka FDA NDI o ʻAmelika Hui Pū ʻIa e hiki ke hoʻohana kūhelu ʻia kāna mea maka NMN i ka hana ʻana, kūʻai aku a me ka hoʻolaha ʻana i nā mea hoʻohui meaʻai ma ʻAmelika Hui Pū ʻIa, a hiki ke loaʻa ma ka pūnaewele mana o ka FDA ma ke ʻano he mea hoʻohui meaʻai hou, helu 1247.
ʻO FDA NDI ka ʻōnaehana hōʻoia koʻikoʻi loa ma ka mākeke US. ʻO ka loaʻa ʻana o kēia palapala hōʻoia ʻaʻole wale ia he palekana a me ka maikaʻi o nā huahana a Shangke Bio.ʻike nui ʻia, akā he mea kōkua nō hoʻi i ka hoʻomohala mau ʻana o ka ʻoihana NMN i ka wā lōʻihi.
| Inoa Kemika | ʻO ka β-Nicotinamide Mononucleotide |
| Nā huaʻōlelo like | NICOTINAMIDE-1-IUM-1-BETA-D-RIBOFURANOSIDE 5'-PHOSPHATE |
| Helu CAS | 1094-61-7 |
| Kaumaha Molekala | 334.22 |
| Formula Molekala | C11H15N2O8P |
| EINECS号: | 214-136-5 |
| Kiko heheʻe | 166 °C (dec.) |
| mahana mālama | -20°C |
| ka hiki ke hoʻoheheʻe ʻia | DMSO (ʻUʻuku, Hoʻomehana ʻia), Methanol (ʻUʻuku), Wai (ʻUʻuku) |
| palapala | Paʻa |
| kala | Keʻokeʻo a Melemele |
| Merck | 13,6697 |
| BRN | 3570187 |
| Paʻa: | Hygroscopic loa |
| ʻInChIKy | DAYLJWODMCOQEW-TURQNECASA-N |
| Mea Hoʻāʻo | Nā kikoʻī |
| helehelena | Keʻokeʻo a i ka pauka kristal keʻokeʻo |
| Ka nui o ka sodium | ≤1% |
| ka waiwai pH (100mg/ml) | 2.0~4.0 |
| Maʻemaʻe | ≥99.0% |
| Ka nui o ka wai | ≤1% |
| Nā metala kaumaha | <10ppm |
| ʻArsenika | <0.5ppm |
| Ke alakaʻi | <0.5ppm |
| Mereki | <0.1ppm |
| Kadmium | <0.5ppm |
| Koena hoʻoheheʻe | ʻEtanola≤1000ppm |
| Ka Helu Holoʻokoʻa o nā Microbial Aerobic | <750cfu/g |
| Hū a me ka ʻōpala | <25cfu/g |
| Koliform holoʻokoʻa | ≤0.92MPN/g |
| ʻO E. Coli | Maikaʻi ʻole |
| Salmonella | Maikaʻi ʻole |
| ʻO Staph. Aureus | Maikaʻi ʻole |
| Hoʻāʻo (ma ke kumu anhydrous) | ≥99.0% |
| Ka helu sieving | ≥95% |
| Ka nui o ka nui | Hōʻike no ka ʻike |
Pūʻolo:ʻŌmole, ʻeke pepa alumini, 25kg/Papa Kālā, a i ʻole e like me ke koi a ka mea kūʻai aku.
Kūlana Mālama:E mālama i loko o nā pahu paʻa a pale i ka māmā, no ka mālama lōʻihi e mālama ma 2~8°C a i ʻole ma lalo.
ʻO Nicotinamide Mononucleotide (NMN) kahi mana hou o ka huaora B3 he mea mua ia o NAD+ (Nicotinamide Adenine Dinucleotide). ʻO NMN ka mea hoʻihoʻi NAD+ cellular mua i hōʻoia ʻia he pono e hoʻihoʻi i nā cell in vivo.
ʻO Nicotinamide Adenine Dinucleotide (NAD) kekahi o nā molekala koʻikoʻi a hoihoi loa i ke kino. Pono ia no nā hopena enzymatic ma mua o 500 a hoʻokani i nā kuleana koʻikoʻi i ka hoʻoponopono ʻana i nā kaʻina hana olaola nui (Ansari lāua ʻo Raghava, 2010). Ma luna o nā mea a pau, hiki iā ia ke ʻae iā mākou e ola olakino a lōʻihi.
Loaʻa ka Nicotinamide Adenine Dinucleotide (NAD) ma kona ʻano oxidized (NAD+) a i ʻole ke ʻano hoʻemi ʻia (NADH), ʻo ia nā cofactors koʻikoʻi o kekahi mau oxireductases.
ʻO SyncoZyems ka mea mua e loaʻa i ka FDA NDI NMN i ʻae ʻia e ka ʻoihana hana mea maka, e hōʻike ana i ke kūlana o ka FDA e ʻae ana iā NMN ma ke ʻano he ʻano mea hou e hiki ke hoʻomaka e ʻae ʻia a ʻae ʻia no nā mea hoʻohui meaʻai ma ʻAmelika Hui Pū ʻIa.
