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ʻO ka phosphoryalse nucloside (NP)
E pili ana i ka phosphoryalse nucleoside
Aia he 3 ʻano o nā huahana enzyme NP (Helu e like me ES-NP-101 ~ ES-NP-103) i hoʻomohala ʻia e SyncoZymes. ʻO ES-NP-101 ka purine nucleoside phosphorylase, ʻo ES-NP-102 a me ES-NP-103 ka pyrimidine nucleoside phosphorylase. Hiki i ka Nucleosidephosphorylase ke hoʻokaʻawale i nā nucleosides i nā kumu a me ka pentose phosphate. Hiki ke hoʻokaʻawale ʻia ka Nucleoside phosphorylase i ka purine nucleoside phosphorylase a me ka pyrimidine nucleoside phosphorylase e like me ka makemake o nā kumu nucleoside. Hiki i ka Purine nucleoside phosphorylase ke hoʻololi i ka adenosine i adenine, inosine i hypoxanthine, guanosine i guanine, a hana i ka ribose phosphate i ka manawa like. Hiki i ka Pyrimidine nucleoside phosphorylase ke hoʻololi i ka uridine i uracil a hana i ka ribose phosphate.
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ʻO ka Hydroaminase (HAM)
E pili ana i ka Hydroaminase
Aia he 2 ʻano huahana enzyme HAM (Helu e like me ES-HAM-101 ~ ES-HAM-102) i hoʻomohala ʻia e SyncoZymes. Hiki i ka HAM ke hoʻoulu i ka ammoniation o ka waikawa enoic a i ʻole kāna mau derivatives e hana i nā waikawa amino chiral. Hiki ke hoʻohana ʻia ka HAM e synthesize i nā waikawa amino chiral (a i ʻole nā amino chiral) mai nā waikawa enoic (a i ʻole alkenes). Pono ka mea hāʻawi ammonia, e like me ka wai ammonia a i ʻole ka paʻakai ammonium.
ʻAno hana catalytic hydroaminase
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CALB i hoʻopaʻa ʻia
KALB
Hoʻopuka ʻia ka Recombinant Lipase B mai Candida antarctica (CALB) ma o ka fermentation i lalo me ka Pichia pastoris i hoʻololi ʻia i ka genetically.
Hiki ke hoʻohana ʻia ʻo CALB i ka esterification catalytic phase wai a i ʻole ka organic phase, esterolysis, transesterification, ring opening polyester synthesis, aminolysis, hydrolysis of amides, acylation of amines a me ka hopena hoʻohui.
Loaʻa iā CALB ke koho chiral kiʻekiʻe a me ke koho kūlana, no laila hiki ke hoʻohana nui ʻia i ka hana ʻaila, ka meaʻai, nā lāʻau lapaʻau, nā mea hoʻonani a me nā ʻoihana kemika ʻē aʻe.
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ʻO ka NADH oxidase (NOX)
E pili ana i ka NADH oxidase
ES-NOX (NADH oxidase): Hoʻoulu ka NOX i ka oxidation o NADH i NAD+, a no ka oxidoreductase. I ke kaʻina hana o ka oxidation, pono ʻo O2 ma ke ʻano he oxidant, a hoʻemi ʻia i H2O a i ʻole H2O2. Aia he 4 ʻano o nā huahana enzyme NOX (ES-NOX-101~ES-NOX-104) i hoʻomohala ʻia e kā mākou hui, hiki ke hoʻohana ʻia no ka hana hou ʻana o ka oxidation o ka coenzyme NAD+.
ʻAno hana catalytic:
or
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ʻO ka lyase phenylalanine ammonia (PAL)
E pili ana i ka lyase ammonia Phenylalanine
ES-PAL: He papa o nā enzymes e hoʻoulu ai i ka deamination pololei o L-phenylalanine i ka waikawa trans-cinnamic. Ua hoʻomohala ʻo Syncozymes i 10 mau mea o ka phenylalanine ammonia lyase (i helu ʻia ʻo ES-PAL-101 ~ ES-PAL-110), hiki ke hoʻohana ʻia i ka deamination a i ʻole ka hopena hoʻohuli o ka phenylalanine a me kāna mau derivatives.
ʻAno hana catalytic:
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ʻO Catalase (CAT)
E pili ana iā Catalase
ES-CAT (Catalase): hoʻoulu i ka hoʻoheheʻe ʻana o H2O2 i oxygen a me ka wai. Loaʻa nui ia i loko o ka mitochondria, endoplasmic reticulum, akepaʻa holoholona a me nā ʻulaʻula koko, ʻoi aku hoʻi i loko o ke akepaʻa ma ke kiʻekiʻe o ka hoʻohuihui ʻana, e hāʻawi ana i ka hana pale antioxidant no ke kino. I ka biocatalysis, hoʻohana nui ʻia ia e wehe i ka hopena hydrogen peroxide a hōʻemi i ka pale ʻana a me ka hoʻopau ʻana o ka enzyme e ka hydrogen peroxide. Hoʻokahi wale nō ʻano o nā huahana enzyme CAT i hoʻomohala ʻia e SyncoZymes (Helu e like me ES-CAT).
ʻAno hana catalytic:
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Lysine oxidase (LO)
E pili ana iā Lysine oxidase
ES-LO (Lysine oxidase): hoʻoulu i ka oxidation o L-lysine i ka 6-amino-2-oxohexanoic acid (a i ʻole kona lactone). Hoʻokahi wale nō ʻano huahana enzyme LO (Helu e like me ES-LO) i hoʻomohala ʻia e SyncoZymes.
ʻAno hana catalytic:
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ʻO Phosphokinase (PKase)
E pili ana i ka Phosphokinase
ES-PKase (Phosphokinase): hoʻoulu i ka hoʻoili ʻana o nā hui phosphate ma ATP i nā hui ʻē aʻe. Hoʻoulu pū ia i ka hoʻoili ʻana o nā hui phosphate ma nā nucleosides ʻē aʻe o ka triphosphate i kekahi manawa. Pono ka hapa nui o nā kinases i nā ion metala divalent e komo i ka hopena (ma ke ʻano maʻamau ʻo Mg2+). Aia he 21 ʻano o nā huahana enzyme PKase (Helu e like me ES-PKase101 ~ ES-PKase-121) i hoʻomohala ʻia e SyncoZymes.
ʻAno hana catalytic:
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ʻO ke Cyclooxygenase (COX)
E pili ana i ka Cyclooxygenase
ʻO ES-COX (Cyclooxygenase): hoʻoulu i ka hoʻololi ʻana o nā pilina C=C i epoxide. Aia he 11 mau ʻano huahana enzyme COX (Helu e like me ES-COX101 ~ ES-COX-111) i hoʻomohala ʻia e SyncoZymes. Wahi a nā ʻano hana catalytic like ʻole, ua māhele ʻia ka COX o SyncoZymes i haloperoxidase a me styrene monooxygenase. No haloperoxidase ʻo ES-COX101, 102, 107-111, ʻoiai ʻo ES-COX103-106 no styrene monooxygenase.
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ʻO ka Cyclohexanone monooxygenase (CHMO)
E pili ana i ka Cyclohexanone monooxygenase
ʻO ES-CHMO (Cyclohexanone monooxygenase): kahi Baeyer Villiger monooxygenase (BVMO) me ka cyclohexanone ma ke ʻano he substrate, hiki ke hoʻololi i ka cyclohexanone i cyclohexanol me ka hoʻohana ʻana i ka oxygen.
He ʻano enzyme ia e hilinaʻi ana i ka flavin. Hoʻemi ʻia ka flavin i oxidized ʻia i flavin ma o ke kaʻina hana o ka hoʻemi ʻana i ka coenzyme II (NADPH) no ka oxidation aʻe. No laila, pono ka cofactor NADPH i ka kaʻina hana flavin. Hoʻokahi wale nō ʻano huahana enzyme CHMO (Helu e like me ES-CHMO101) i hoʻomohala ʻia e SyncoZymes, hiki ke hoʻohana ʻia e oxidize i ka cyclohexanone i cyclohexanone.
ʻAno hana catalytic:
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ʻO ka reductase waikawa carboxylic (CAR)
E pili ana i ka reductase waikawa Carboxylic
ES-CAR (Carboxylic acid reductase): hoʻoulu i ka hōʻemi ʻana o ka hui carboxyl i ka hui aldehyde. I ke kaʻina hana catalytic, pono ka hoʻoulu ʻana o ATP a me ka coenzyme NADPH ma ke ʻano he mau mea lawe hydrogen. Aia he 2 ʻano o nā huahana enzyme CAR (Helu e like me ES-CAR101 ~ ES-CAR-102) i hoʻomohala ʻia e SyncoZymes.
ʻAno hana catalytic:
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ʻO ka phenylalanine dehydrogenase (PDH)
E pili ana i ka Phenylalanine dehydrogenase
ES-PDH: He papa o ka oxidoreductase. Hiki i ka hopena maikaʻi ke hoʻoulu i ka deamination oxidative o ka paʻakai L phenylalanine i ke alo o NAD e hana i ka paʻakai phenylpyruvate, a hiki i ka hopena hope ke hoʻoulu i ka synthesis o ka paʻakai amino acid like mai ka paʻakai phenylpyruvate. Ua hoʻomohala ʻo Syncozymes i 8 mau mea o ka phenylalanine dehydrogenase (i helu ʻia ʻo ES-PDH-101~ES-PDH-108). Hiki ke hoʻohana ʻia ʻo ES-PDH e hoʻomākaukau i ka paʻakai phenylalanine a i ʻole ka paʻakai amino acid like mai ka paʻakai phenylpyruvic acid a i ʻole nā mea i loaʻa.
ʻAno hana catalytic:
Kelepona Paʻalima/Wechat/WhatsApp: +86-13681683526
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