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Nucloside phosphoryalse (NP)
E pili ana i ka nucleoside phosphoryalse
Aia 3 ʻano huahana enzyme NP (Helu e like me ES-NP-101~ ES-NP-103) i hoʻomohala ʻia e SyncoZymes.ʻO ES-NP-101 ka purine nucleoside phosphorylase, ES-NP-102 a me ES-NP-103 he pyrimidine nucleoside phosphorylase.Hiki i ka Nucleosidephosphorylase ke hoʻoheheʻe i nā nucleosides i nā kumu a me ka pentose phosphate.Hiki ke hoʻokaʻawale ʻia ka Nucleoside phosphorylase i purine nucleoside phosphorylase a me pyrimidine nucleoside phosphorylase e like me ka makemake o nā kumu nucleoside.Hiki i ka purine nucleoside phosphorylase ke hoʻololi i ka adenosine i adenine, inosine i hypoxanthine, guanosine i guanine, a hana i ka ribose phosphate i ka manawa like.Hiki i ka Pyrimidine nucleoside phosphorylase ke hoʻololi i ka uridine i ka uracil a hana i ka ribose phosphate.
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Hydroaminase (HAM)
E pili ana i ka Hydroaminase
Aia 2 ʻano huahana enzyme HAM (Helu e like me ES-HAM-101~ ES-HAM-102) i hoʻomohala ʻia e SyncoZymes.Hiki i ka HAM ke hoʻokaʻawale i ka ammoniation o ka waika enoic a i ʻole nā mea i loaʻa mai e hana i nā waikawa amino chiral.Hiki ke hoʻohana ʻia ka HAM e hoʻohui i nā ʻakika amino chiral (a i ʻole chiral amines) mai nā waikawa enoic (a i ʻole alkenes).Pono ka mea hāʻawi Ammonia, e like me ka wai amonia a i ʻole ka paʻakai ammonium.
Hydroaminase catalytic pane ʻano
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Hoʻokuʻu ʻia ʻo CALB
CALB
Hana ʻia ʻo Recombinant Lipase B mai Candida antarctica (CALB) e ka fermentation submerged me Pichia pastoris i hoʻololi ʻia.
Hiki ke hoʻohana ʻia ʻo CALB i loko o ka wai a i ʻole ka organik phase catalytic esterification, esterolysis, transesterification, ring opening polyester synthesis, aminolysis, hydrolysis of amides, acylation of amines a me ka hoʻohui ʻana.
Loaʻa ka CALB me ke koho chiral kiʻekiʻe a me ke koho kūlana, no laila hiki ke hoʻohana nui ʻia i ka hana ʻaila, ka meaʻai, ka lāʻau lapaʻau, nā mea hoʻonaninani a me nā ʻoihana kemika ʻē aʻe.
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NADH oxidase (NOX)
E pili ana i ka NADH oxidase
ES-NOX (NADH oxidase): NOX hoʻopale i ka oxidation o NADH i NAD +, a no ka oxidoreductase.I ke kaʻina o ka oxidation, pono ʻo O2 ma ke ʻano he oxidant, a hoʻemi ʻia i H2O a i ʻole H2O2.Aia he 4 mau ʻano huahana enzyme NOX (ES-NOX-101~ES-NOX-104) i hoʻomohala ʻia e kā mākou hui, hiki ke hoʻohana ʻia no ka hoʻōla hou ʻana o ka coenzyme NAD +.
ʻAno hoʻopā catalytic:
or
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Phenylalanine ammonia lyase (PAL)
No Phenylalanine ammonia lyase
ES-PAL: He papa o nā enzymes e hoʻopololei i ka hoʻokaʻawale pololei ʻana o L-phenylalanine i ka waikawa transcinnamic.Hoʻokumu ʻo Syncozymes i 10 mau mea o ka phenylalanine ammonia lyase (helu ʻia ʻo ES-PAL-101~ES-PAL-110), hiki ke hoʻohana ʻia i ka deamination a i ʻole ka hoʻohuli ʻana o ka phenylalanine a me kāna mau mea.
ʻAno hoʻopā catalytic:
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Catalase (CAT)
No Catalase
ES-CAT (Catalase): hoʻopaʻa i ka decomposition o H2O2 i oxygen a me ka wai.Loaʻa ia ma ka mitochondria, endoplasmic reticulum, nā holoholona a me nā ʻulaʻula ʻulaʻula, ʻoi aku hoʻi i loko o ke ake i ke kiʻekiʻe kiʻekiʻe, e hāʻawi ana i ka hana pale antioxidant no ke kino.I ka biocatalysis, hoʻohana nui ia e wehe i ka hopena o ka hydrogen peroxide a hoʻemi i ka inhibition a me ka inactivation o ka enzyme e ka hydrogen peroxide.Hoʻokahi wale nō ʻano huahana enzyme CAT i hoʻomohala ʻia e SyncoZymes (Number like ES-CAT).
ʻAno hoʻopā catalytic:
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Lysine oxidase (LO)
E pili ana iā Lysine oxidase
ES-LO (Lysine oxidase): hoʻopaʻa i ka hoʻopaʻa ʻana o L-lysine i 6-amino-2-oxohexanoic acid (a i ʻole kāna lactone).Hoʻokahi wale nō ʻano huahana enzyme LO (Helu e like me ES-LO) i hoʻomohala ʻia e SyncoZymes.
ʻAno hoʻopā catalytic:
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Phosphokinase (PKase)
E pili ana i ka Phosphokinase
ES-PKase (Phosphokinase): hoʻopale i ka hoʻololi ʻana o nā pūʻulu phosphate ma ATP i nā pūhui ʻē aʻe.Hoʻopili pū ia i ka hoʻoili ʻana o nā pūʻulu phosphate ma nā nucleosides o triphosphate i kekahi manawa.Pono ka hapa nui o nā kinase i nā ion metala divalent no ke komo ʻana i ka hopena (maʻamau Mg2+).He 21 ʻano huahana enzyme PKase (Helu e like me ES-PKase101~ ES-PKase-121) i hoʻomohala ʻia e SyncoZymes.
ʻAno hoʻopā catalytic:
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Cyclooxygenase (COX)
E pili ana iā Cyclooxygenase
ES-COX (Cyclooxygenase): hoʻolalelale i ka hoʻololi ʻana o nā paʻa C=C i epoxide.He 11 ʻano huahana enzyme COX (Helu e like me ES-COX101~ ES-COX-111) i hoʻomohala ʻia e SyncoZymes.Wahi a nā ʻano catalytic like ʻole, ua māhele ʻia ka COX o SyncoZymes i haloperoxidase a me styrene monooxygenase.ʻO ES-COX101, 102, 107-111 no ka haloperoxidase, aʻo ES-COX103-106 no ka styrene monooxygenase.
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Cyclohexanone monooxygenase (CHMO)
E pili ana iā Cyclohexanone monooxygenase
ES-CHMO (Cyclohexanone monooxygenase): kahi Baeyer Villiger monooxygenase (BVMO) me ka cyclohexanone ma ke ʻano he substrate, hiki ke hoʻokahe i ka cyclohexanone i cyclohexanol me ka hoʻohana ʻana i ka oxygen.
He ʻano enzyme pili flavin.Hoʻemi ʻia ka flavin oxidized i flavin ma o ka pōʻaiapuni o ka hoʻemi ʻana i ka coenzyme II (NADPH) no ka hoʻonā ʻana aʻe.No laila, pono ka cofactor NADPH i ka pōʻai flavin.Hoʻokahi wale nō ʻano huahana enzyme CHMO (Helu e like me ES-CHMO101) i hoʻomohala ʻia e SyncoZymes, hiki ke hoʻohana ʻia e oxidize cyclohexanone i cyclohexanone.
ʻAno hoʻopā catalytic:
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E-mail:lchen@syncozymes.com
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Carboxylic acid reductase (CAR)
E pili ana i ka Carboxylic acid reductase
ES-CAR (Carboxylic acid reductase): hoʻolalelale i ka hōʻemi ʻana o ka pūʻulu carboxyl i ka pūʻulu aldehyde.I ke kaʻina hana catalytic, koi ʻia ka hoʻoulu ʻana o ATP a me ka coenzyme NADPH e like me nā mea lawe hydrogen.Aia ʻelua ʻano huahana enzyme CAR (Helu e like me ES-CAR101~ ES-CAR-102) i hoʻomohala ʻia e SyncoZymes.
ʻAno hoʻopā catalytic:
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E-mail:lchen@syncozymes.com
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Transaldolase (TAL)
No Transaldolase
ʻO ES-TAL (Transaldolase): pili nui i nā transaldolases threonine, hiki ke hoʻololi i ka hopena e synthesize β-hydroxyphenylalanine derivatives me threonine a me benzaldehyde derivatives.ʻO TAL ka enzyme pili i ka PLP.Hoʻokahi wale nō ʻano huahana enzyme TAL (Helu e like me ES-TAL101) i hoʻomohala ʻia e SyncoZymes, hiki ke hoʻohana ʻia no ka hoʻohui ʻana i ka β-hydroxyphenylalanine a me kāna mau mea.
ʻAno hoʻopā catalytic:
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