Kiʻi i hōʻike ʻia ʻo Cyclooxygenase (COX)

ʻO ke Cyclooxygenase (COX)

Wehewehe Pōkole:

E pili ana i ka Cyclooxygenase

ʻO ES-COX (Cyclooxygenase): hoʻoulu i ka hoʻololi ʻana o nā pilina C=C i epoxide. Aia he 11 mau ʻano huahana enzyme COX (Helu e like me ES-COX101 ~ ES-COX-111) i hoʻomohala ʻia e SyncoZymes. Wahi a nā ʻano hana catalytic like ʻole, ua māhele ʻia ka COX o SyncoZymes i haloperoxidase a me styrene monooxygenase. No haloperoxidase ʻo ES-COX101, 102, 107-111, ʻoiai ʻo ES-COX103-106 no styrene monooxygenase.

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Leka uila:lchen@syncozymes.com

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Nā kikoʻī huahana

Nā Lepili Huahana

E pili ana i ka Cyclooxygenase:

ʻAno hana catalytic:

ʻO ka Haloperoxidase:

ʻO ka styrene monooxygenase:

ʻIke Huahana:

Nā ʻenzyme	Kōmike Huahana	Nā kikoʻī
Pauka ʻenzyme	ES-COX-101~ ES-COX-110	he set o 10 NADH Cyclooxygenase, 50 mg kēlā me kēia 10 mau mea * 50mg / mea, a i ʻole ka nui ʻē aʻe

Nā Pōmaikaʻi:

★ Kiʻekiʻe ke ʻano kikoʻī o ka substrate.
★ Koho chiral ikaika.
★ Hoʻololi kiʻekiʻe.
★ Emi nā huahana ʻaoʻao.
★ Nā kūlana pane iki.
★ Mālama i ke kaiapuni.

Nā kuhikuhi no ka hoʻohana ʻana:

➢ ʻO ka maʻamau, ʻo ka ʻōnaehana hana haloperoxidase e komo pū ana me: substrate, buffer, enzyme, H2O2 a me ka ion halogen. ʻO ka ʻōnaehana hana Styrene monooxygenase e komo pū ana me ka substrate, buffer, enzyme, coenzyme a me ka ʻōnaehana hana hou coenzyme
➢ Pono e hoʻohui hope ʻia ʻo COX i loko o ka ʻōnaehana hana, ma hope o ka hoʻoponopono ʻia ʻana o ka pH a me ka mahana i ke kūlana hana.

Nā Laʻana Noi:

Laʻana 1 (Hana ʻia nā mea i loaʻa mai ka epoxy styrene mai nā mea i loaʻa mai ka styrene)⁽¹⁾:

Nānā: ua manaʻo ʻia nā laʻana noi a me nā kuhikuhi e hōʻike i ka laulā o ka noi o COX no ka maʻalahi o ka hoʻomaopopo ʻana, a ʻaʻole kūlike me ka enzyme kikoʻī o SyncoZymes.