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Oxynitrilase (HNL)
E pili ana i nā oxynitrilase
ES-HNLs: He enzyme papa e hoʻopololei ana i ka hoʻohui ʻana o HCN i nā aldehydes (ketones) no ka loaʻa ʻana o nā ʻona ʻona cyanide ʻano R a i ʻole S, hiki ke hoʻololi maʻalahi i nā ʻano lāʻau lapaʻau a i ʻole nā lāʻau waena ma o ke ʻano kemika.
Aia he 29 ʻano huahana oxynitrilase (Helu e like me ES-HNL-101～ES-HNL-129) i hoʻomohala ʻia e SyncoZymes.He mea hana pono ka SZ-HNL i ka regio- a me ka stereo- selective synthesis o (R) -cyanohydrins a i ʻole (S) -cyanohydrins mai nā ʻano mea ʻala like ʻole, aliphatic a heterocyclic aldehydes a i ʻole ketones.
ʻAno hoʻopā catalytic:
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E-Mail:lchen@syncozymes.com
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Nitro reductase (NTR)
E pili ana i ka nitro reductase
ES-NTRs: He mau flavoenzymes ka mea e hoʻoemi i ka NAD(P)H i hilinaʻi ʻia o nā pūʻulu nitro ma nā pūhui nitroaromatic a me nitroheterocyclic i ka hydroxylamino a/a i nā derivatives amino.Hoʻohana nui ʻia lākou i ka synthesis organik o ka aromatic hydroxylamine a me ka aromatic amine, ka maʻi tumora, ka ʻike biological a me ka hoʻohaʻahaʻa ʻana i nā mea haumia kaiapuni.Aia he 12 ʻano o nā huahana Nitro reductase (NTR) (Helu e like me ES-NTR-101~ES-NTR-112) i hoʻomohala ʻia e SyncoZymes.
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E-Mail:lchen@syncozymes.com
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Aldolase (DERA)
Nā ES-DERA: Hiki ke hoʻopili pono i ka hoʻohui stereoselective o nā ketone hāʻawi i nā aldehydes i loaʻa.Eia kekahi, hiki ke hana ʻia ka hopena i loko o ka wai wai o ka pH neutral me ka ʻole o nā hana pale kūikawā.Aia lākou i ka papa I aldolase, ka mea i hoʻokumu i ke kumu Shiff i ka hana catalytic.Hoʻopili paʻa ʻia ka substrate me ka hui amino o ka pae hana e hoʻomaka ai i ka haki ʻana a me ka hoʻokumu ʻana o ka paʻa.ʻO ka ʻokoʻa ma waena o nā DERA a me nā aldolase ʻē aʻe, ʻo nā substrates a lākou e hoʻopaʻa ai he aldehydes a hiki ke hoʻomau i ka condensation aldehydes.
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E-Mail:lchen@syncozymes.com
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Cytochrome P450 monooxygenase (CYP)
E pili ana iā CYP
ES-CYPs: He papa o nā enzymes redox me mercaptan-heme ma ke ʻano he kikowaena hana e hoʻoikaika i ka hoʻoili oxygen.He mau oxygenases hope lākou a pono lākou i ka heme e hoʻāla ai i ka oxygen.
Cytochrome P450 monooxygenase catalyze i ka oxidation, epoxidation a me ka hydroxylation o alkyl, hydroxylation a me ka oxidation o ka amonia, oxidation o sulfur, dealkylation (oxygen, sulfur, amonia), oxidative dehydrogenation, deamination a me ka dehalogenation.
He 8 mau ʻano huahana cytochrome P450 monooxygenase (Helu e like me ES-CYP-101～ES-CYP-108) i hoʻomohala ʻia e SyncoZymes.Mobile/Wechat/WhatsApp: +86-13681683526
E-Mail:lchen@syncozymes.com
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Alcohol oxidase (AOX)
E pili ana i ka waiʻona oxidase
ES-AOXs: Hiki i kēia mau enzymes ke hoʻopololei i ka hoʻoheheʻe ʻia o nā momona momona a i ʻole nā aryl-alcohols e hana i nā aldehydes.Hoʻohana lākou i ka oxygen molekula akā ʻaʻole koi i kahi cofactor i hoʻohui ʻia i waho, a hana ʻia ka hydrogen peroxide.
Aia he 6 mau ʻano huahana oxidases alcohol (Helu e like me ES-AOX-101~ES-AOX-106) i hoʻomohala ʻia e SyncoZymes.Makemake ʻo ES-AOX101 a me ES-AOX102 i nā substrate waiʻona aliphatic, ʻo ES-AOX103~ ES-AOX105 makemake i nā substrate waiʻona ʻala, a ʻo ES-AOX106 ka cholesterol oxidase.He mea hana pono ka SZ-AOX no ka hoʻopaʻa ʻana i nā ʻona momona a i ʻole nā aryl-alcohols e hana i nā aldehydes.
ʻAno hoʻopā catalytic:
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E-Mail:lchen@syncozymes.com
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D-Amino acid dehydrogenase (D-AADH)
E pili ana i ka D-Amino acid dehydrogenase
ES-D-AADH (D-Amino acid dehydrogenase): he enzyme hiki ke hoʻemi i ka waika 2-keto i loko o ka waika D-amino like.Pono ka hopena i ka NADP(H) a me ka mea hāʻawi ammonia inorganic (e like me ka ammonia a i ʻole ammonium ion).He 17 mau ʻano D-amino acid dehydrogenases (Helu e like me ES-DAADH-101~ ES-DAADH-117) i hoʻomohala ʻia e SyncoZymes.
ʻAno hoʻopā catalytic:
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E-Mail:lchen@syncozymes.com
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Esterase&Lipase (PLE&CALB)
E pili ana iā Esterase&Lipase
Nā ES-PLE: He papa o nā hydrolases e hoʻoikaika i ka hoʻokumu ʻana a me ka haki ʻana o nā mea paʻa ester.Hiki iā lākou ke komo i loko o nā ʻano hopena biochemical, e like me ka esterification, transesterification a me ka hydrolysis.Hoʻohana nui ʻia lākou i nā kula he nui e like me ka hoʻoili ʻana i ka meaʻai, ʻoihana kemika, biomedicine, lāʻau chiral a me ka mālama kaiapuni.
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E-Mail:lchen@syncozymes.com
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Epoxide hydrolase (EH)
E pili ana i ka epoxide hydrolase
ʻO ka EH ka eter hydrolase e hoʻopololei i ka stereoselective hydrolysis o racemic epoxides e hana i ka 1, 2-diol a me ka optically active epoxides, hiki ke hoʻohana ʻia no ka hoʻonā chiral o nā epoxides a i ʻole ka hoʻomākaukau ʻana i nā diols chiral.Hoʻohana nui ʻia lākou i ka lāʻau lapaʻau a me nā ʻoihana ʻē aʻe.Aia 3 ʻano huahana epoxide hydrolases (Helu e like me ES-EH-101～ES-EH-103) i hoʻomohala ʻia e SyncoZymes.He mea hana pono ka ES-EH no ka hoʻopili ʻana i ka synthesis o nā waiʻona chiral ma o ka stereoselective hydrolysis o aliphatic a me nā epoxide aromatic.
ʻAno hoʻopā catalytic:
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E-Mail:lchen@syncozymes.com
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Formate dehydrogenase (FDH)
E pili ana i ka Formate dehydrogenase
ES-FDH (Formate dehydrogenase): FDH catalyze i ka dehydrogenation o ka ammonium formate e hana i carbon dioxide a me ka amonia, a e hoemi i ka NAD i NADH me NAD ma ke ano he electron receptor.Hoʻohana pinepine ʻia ka FDH no ka hana hou ʻana o ka coenzyme NADH.Aia he 4 mau ʻano huahana enzyme FDH (ES-FDH-101~ES-FDH-104) i hoʻomohala ʻia e SyncoZymes, ma waena o ES-FDH102 ka hana kiʻekiʻe loa a ʻo ia ka FDH i manaʻo nui ʻia.
ʻAno hoʻopā catalytic:
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E-Mail:lchen@syncozymes.com
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Glucose dehydrogenase (GDH)
E pili ana i ka Glucose dehydrogenase
ES-GDH (Glucose dehydrogenase): GDH e hoʻopaʻa i ka dehydrogenation o ka glucose e hana ai i ka ʻakika gluconic (lactone), a e hoʻemi i ka NAD(P)+ i NAD(P)H, me ka NAD(P)+ ma ke ʻano he electron receptor.Hoʻohana pinepine ʻia ʻo GDH no ka hana hou ʻana o ka coenzyme NAD(P)H i nā māla biocatalysis me nā enzyme nui ʻē aʻe.Aia he 10 mau ʻano huahana enzyme GDH (ES-GDH-101~ES-GDH-110) i hoʻomohala ʻia e SyncoZymes, ma waena o ES-GDH110 ka hana kiʻekiʻe loa a ʻo ia ka GDH i manaʻo nui ʻia.
ʻAno hoʻopā catalytic:
Mobile/Wechat/WhatsApp: +86-13681683526
E-Mail:lchen@syncozymes.com
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Monoamine oxidase (MAO)
E pili ana i ka Monoamine oxidase
ES-MAO(Monoamine oxidase): Hoʻopili ʻo MAO i ka deamination oxidative o nā monoamines e hana i ka hydrogen peroxide, ammonia a me nā aldehydes pili.I ke kaʻina hana catalytic, pono ka oxygen ma ke ʻano he oxidant.He 6 ʻano huahana enzyme MAO (Helu e like me ES-MAO-101～ES-MAO-106) i hoʻomohala ʻia e SyncoZymes, hiki ke hoʻohana ʻia i ka deamination oxidative o nā pūhui monoamine.
ʻAno hoʻopā catalytic:
Mobile/Wechat/WhatsApp: +86-13681683526
E-Mail:lchen@syncozymes.com
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Lactate Dehydrogenase (LDH)
E pili ana i ka Lactate dehydrogenase
Aia 1 ʻano huahana enzyme LDH (Helu e like me ES-LDH) i hoʻomohala ʻia e SyncoZymes.Hiki i ka LDH ke hoʻoemi i ka pyruvate i ka L-lactic acid, a i ʻole ka hōʻemi ʻana i nā waikawa α-keto like ʻole.I ke kaʻina hana o ka catalysis, pono ʻo NADH ma ke ʻano he hydrogen transporter.
ʻAno ʻano hoʻohālikelike lactate dehydrogenasecatalytic
Mobile/Wechat/WhatsApp: +86-13681683526
E-Mail:lchen@syncozymes.com
