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ʻO Phosphokinase (PKase)
E pili ana i ka Phosphokinase
ES-PKase (Phosphokinase): hoʻoulu i ka hoʻoili ʻana o nā hui phosphate ma ATP i nā hui ʻē aʻe. Hoʻoulu pū ia i ka hoʻoili ʻana o nā hui phosphate ma nā nucleosides ʻē aʻe o ka triphosphate i kekahi manawa. Pono ka hapa nui o nā kinases i nā ion metala divalent e komo i ka hopena (ma ke ʻano maʻamau ʻo Mg2+). Aia he 21 ʻano o nā huahana enzyme PKase (Helu e like me ES-PKase101 ~ ES-PKase-121) i hoʻomohala ʻia e SyncoZymes.
ʻAno hana catalytic:
Kelepona Paʻalima/Wechat/WhatsApp: +86-13681683526
Leka uila:lchen@syncozymes.com
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ʻO ke Cyclooxygenase (COX)
E pili ana i ka Cyclooxygenase
ʻO ES-COX (Cyclooxygenase): hoʻoulu i ka hoʻololi ʻana o nā pilina C=C i epoxide. Aia he 11 mau ʻano huahana enzyme COX (Helu e like me ES-COX101 ~ ES-COX-111) i hoʻomohala ʻia e SyncoZymes. Wahi a nā ʻano hana catalytic like ʻole, ua māhele ʻia ka COX o SyncoZymes i haloperoxidase a me styrene monooxygenase. No haloperoxidase ʻo ES-COX101, 102, 107-111, ʻoiai ʻo ES-COX103-106 no styrene monooxygenase.
Kelepona Paʻalima/Wechat/WhatsApp: +86-13681683526
Leka uila:lchen@syncozymes.com
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ʻO ka Cyclohexanone monooxygenase (CHMO)
E pili ana i ka Cyclohexanone monooxygenase
ʻO ES-CHMO (Cyclohexanone monooxygenase): kahi Baeyer Villiger monooxygenase (BVMO) me ka cyclohexanone ma ke ʻano he substrate, hiki ke hoʻololi i ka cyclohexanone i cyclohexanol me ka hoʻohana ʻana i ka oxygen.
He ʻano enzyme ia e hilinaʻi ana i ka flavin. Hoʻemi ʻia ka flavin i oxidized ʻia i flavin ma o ke kaʻina hana o ka hoʻemi ʻana i ka coenzyme II (NADPH) no ka oxidation aʻe. No laila, pono ka cofactor NADPH i ka kaʻina hana flavin. Hoʻokahi wale nō ʻano huahana enzyme CHMO (Helu e like me ES-CHMO101) i hoʻomohala ʻia e SyncoZymes, hiki ke hoʻohana ʻia e oxidize i ka cyclohexanone i cyclohexanone.
ʻAno hana catalytic:
Kelepona Paʻalima/Wechat/WhatsApp: +86-13681683526
Leka uila:lchen@syncozymes.com
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ʻO ka reductase waikawa carboxylic (CAR)
E pili ana i ka reductase waikawa Carboxylic
ES-CAR (Carboxylic acid reductase): hoʻoulu i ka hōʻemi ʻana o ka hui carboxyl i ka hui aldehyde. I ke kaʻina hana catalytic, pono ka hoʻoulu ʻana o ATP a me ka coenzyme NADPH ma ke ʻano he mau mea lawe hydrogen. Aia he 2 ʻano o nā huahana enzyme CAR (Helu e like me ES-CAR101 ~ ES-CAR-102) i hoʻomohala ʻia e SyncoZymes.
ʻAno hana catalytic:
Kelepona Paʻalima/Wechat/WhatsApp: +86-13681683526
Leka uila:lchen@syncozymes.com
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ʻO Eluxadoline Waena methyl 5-(((S)-2-((tert-butoxycarbonyl)amino)-3-(4-carbamoyl-2,6-dimethylphenyl)-N-((S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl)propanamido)methyl)-2-methoxybenzoate
Papa Kuhikuhi Helu SZ-2078
CAS: 1137026-67-5
Maʻemaʻe: 99%
Hoʻohana ʻana iā Eluxadoline
Kelepona Paʻalima/Wechat/WhatsApp: +86-13681683526
Leka uila:lchen@syncozymes.com
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ʻO Eluxadoline Waena (S)-Methyl 2-Methoxy-5-((1-(4-phenyl-1H-imidazol-2-yl)ethylamino)methyl)benzoate
Helu Papa Kuhikuhi SZ-2077
CAS: 1391712-57-4
Maʻemaʻe: 99%
Hoʻohana ʻana iā Eluxadoline
Kelepona Paʻalima/Wechat/WhatsApp: +86-13681683526
Leka uila:lchen@syncozymes.com
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ʻAdapalene Waena 1-(5-bromo-2-methoxy-phenyl)adamantane
Helu Papa Kuhikuhi SZ-1559
CAS: 104224-63-7
Maʻemaʻe: 99%
Hoʻohana ʻia ʻo Adpalene
Kelepona Paʻalima/Wechat/WhatsApp: +86-13681683526
Leka uila:lchen@syncozymes.com
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ʻO ka Eluxadoline Waena (S)-Methyl 2-Methoxy-5-((1-(4-phenyl-1H-imidazol-2-yl)ethylamino)methyl)benzoate waikawa oxalic
Helu Papa Kuhikuhi SZ-2077
CAS: 2046303-09-5
Maʻemaʻe: 99%
Hoʻohana ʻana iā Eluxadoline
Kelepona Paʻalima/Wechat/WhatsApp: +86-13681683526
Leka uila:lchen@syncozymes.com
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ʻO ka Ibrutinib Intermediate (S)-1-Boc-3-hydroxypiperidine
Helu Papa Kuhikuhi SZ-1527
CAS: 143900-44-1
Maʻemaʻe: 99%
Ka hoʻohana ʻana iā Ibrutinib
Kelepona Paʻalima/Wechat/WhatsApp: +86-13681683526
Leka uila:lchen@syncozymes.com
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![ʻO Ibrutinib Waena 3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine](https://cdn.globalso.com/syncozymesnad/3-4-phenoxyphenyl-1H-pyrazolo34-dpyrimidin-4-amine.jpg)
ʻO Ibrutinib Waena 3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Helu Papa Kuhikuhi SZ-2028
CAS: 330786-24-8
Maʻemaʻe: 99%
Ka hoʻohana ʻana iā Ibrutinib
Kelepona Paʻalima/Wechat/WhatsApp: +86-13681683526
Leka uila:lchen@syncozymes.com
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ʻO Ibrutinib Waena 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile
Papa Kuhikuhi Helu SZ-2028-4
CAS: 330792-70-6
Maʻemaʻe: 99%
Hoʻohana 25kg/barela
Kelepona Paʻalima/Wechat/WhatsApp: +86-13681683526
Leka uila:lchen@syncozymes.com
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ʻO ka phenylalanine dehydrogenase (PDH)
E pili ana i ka Phenylalanine dehydrogenase
ES-PDH: He papa o ka oxidoreductase. Hiki i ka hopena maikaʻi ke hoʻoulu i ka deamination oxidative o ka paʻakai L phenylalanine i ke alo o NAD e hana i ka paʻakai phenylpyruvate, a hiki i ka hopena hope ke hoʻoulu i ka synthesis o ka paʻakai amino acid like mai ka paʻakai phenylpyruvate. Ua hoʻomohala ʻo Syncozymes i 8 mau mea o ka phenylalanine dehydrogenase (i helu ʻia ʻo ES-PDH-101~ES-PDH-108). Hiki ke hoʻohana ʻia ʻo ES-PDH e hoʻomākaukau i ka paʻakai phenylalanine a i ʻole ka paʻakai amino acid like mai ka paʻakai phenylpyruvic acid a i ʻole nā mea i loaʻa.
ʻAno hana catalytic:
Kelepona Paʻalima/Wechat/WhatsApp: +86-13681683526
Leka uila:lchen@syncozymes.com
