-
ʻImine reductase (IRED)
E pili ana i ka Imine reductase
ES-IRED: He papa o nā enzymes e hoʻoulu ai i ka hōʻemi ʻana o ka pilina C=N i ka pilina CN. No ka enzyme redox ia, me ka coenzyme NADPH no ka lawe ʻana i ka hydrogen. Wahi a ka makemake chiral o nā huahana, hiki ke hoʻokaʻawale ʻia iā R-IRED a me S-IRED. Ua hoʻomohala ʻo Syncozymes i 15 mau imine reductases (numbIRED ES-IRED-101-ES-IRED-115), hiki ke hoʻohana nui ʻia i ka hōʻemi regioselective a me stereoselective o nā imines e hoʻomākaukau i nā amines chiral.
ʻAno hana catalytic:
Kelepona Paʻalima/Wechat/WhatsApp: +86-13681683526
Leka uila:lchen@syncozymes.com
-
ʻO ka hoʻemi ʻana o ka nitrile (NRED)
E pili ana i ka Nitrile reductase
Aia he 3 ʻano huahana enzyme NRED (Helu e like me ES-NRED101 ~ ES-NRED103) i hoʻomohala ʻia e SyncoZymes. Hiki iā NRED ke hoʻoikaika i ka hōʻemi ʻana o ka hui nitrile i amine. I ke kaʻina hana o ka catalysis, pono ʻo NADPH ma ke ʻano he mea lawe hydrogen.
ʻAno hana catalytic Nitrile reductase
Kelepona Paʻalima/Wechat/WhatsApp: +86-13681683526
Leka uila:lchen@syncozymes.com
-
ʻO ka Leucine Dehydrogenase (LeuDH)
E pili ana i ka Leucine dehydrogenase
Aia kekahi ʻano huahana enzyme LeuDH (Helu e like me ES-LeuDH-101) i hoʻomohala ʻia e SyncoZymes. Hiki iā LeuDH ke hoʻoulu i ka ammoniation reductive o ka 4-methylbutanoic acid (paʻakai) i L-leucine a i ʻole ka oxidation o ka leucine i 4-methylbutanoic acid. Hiki iā ES-LeuDH ke hoʻoulu i ka amination reductive o nā waikawa α-keto me ke ʻano like e hoʻomākaukau i nā derivatives amino acid e pili ana. I ke kaʻina hana o ka catalysis, pono ʻo NADH ma ke ʻano he mea lawe hydrogen.
ʻAno hopena catalytic Leucine dehydrogenase
Kelepona Paʻalima/Wechat/WhatsApp: +86-13681683526
Leka uila:lchen@syncozymes.com
-
ʻO ka Threonine deaminase (TDA)
E pili ana i ka Threonine deaminase
ʻO ES-TDA (Threonine deaminase): kahi protein pyridoxal phosphate e hoʻoulu ai i ka deamination o threonine e hana i ka 2-ketobutyric acid a me ka ammonia. Pono ka Pyridoxal 5-phosphate ma ke ʻano he coenzyme i loko o ka ʻōnaehana catalytic. Hoʻokahi wale nō ʻano huahana enzyme TDA (Helu e like me ES-TDA) i hoʻomohala ʻia e SyncoZymes, hiki ke hoʻohana ʻia e hoʻomākaukau i ka 2-ketobutyric acid a i ʻole kona mau derivatives mai threonine.
ʻAno hana catalytic:
Kelepona Paʻalima/Wechat/WhatsApp: +86-13681683526
Leka uila:lchen@syncozymes.com
-
ʻAmine Dehydrogenase (AmDH)
E pili ana i ka Amine Dehydrogenase
ʻO ES-AmDH (Amine Dehydrogenase): kahi enzyme hiki ke hoʻoulu i ka ammoniation o ka hui carbonyl a hoʻemi iā ia i ka hui amino. He coenzyme ia e hilinaʻi ana i ka NADH, a hana ʻo NADH ma ke ʻano he mea hoʻoili hydrogen. Aia he 4 ʻano o nā huahana enzyme AmDH (Helu e like me ES-AmDH101～ES-AmDH104) i hoʻomohala ʻia e SyncoZymes, hiki ke hoʻohana ʻia i ka regioselective a i ʻole stereoselective reductive amination o nā aldehydes a me nā ketones.
ʻAno hana catalytic:
Kelepona Paʻalima/Wechat/WhatsApp: +86-13681683526
Leka uila:lchen@syncozymes.com
-
ʻO ka phosphoryalse nucloside (NP)
E pili ana i ka phosphoryalse nucleoside
Aia he 3 ʻano o nā huahana enzyme NP (Helu e like me ES-NP-101 ~ ES-NP-103) i hoʻomohala ʻia e SyncoZymes. ʻO ES-NP-101 ka purine nucleoside phosphorylase, ʻo ES-NP-102 a me ES-NP-103 ka pyrimidine nucleoside phosphorylase. Hiki i ka Nucleosidephosphorylase ke hoʻokaʻawale i nā nucleosides i nā kumu a me ka pentose phosphate. Hiki ke hoʻokaʻawale ʻia ka Nucleoside phosphorylase i ka purine nucleoside phosphorylase a me ka pyrimidine nucleoside phosphorylase e like me ka makemake o nā kumu nucleoside. Hiki i ka Purine nucleoside phosphorylase ke hoʻololi i ka adenosine i adenine, inosine i hypoxanthine, guanosine i guanine, a hana i ka ribose phosphate i ka manawa like. Hiki i ka Pyrimidine nucleoside phosphorylase ke hoʻololi i ka uridine i uracil a hana i ka ribose phosphate.
Kelepona Paʻalima/Wechat/WhatsApp: +86-13681683526
Leka uila:lchen@syncozymes.com
-
ʻO ka Hydroaminase (HAM)
E pili ana i ka Hydroaminase
Aia he 2 ʻano huahana enzyme HAM (Helu e like me ES-HAM-101 ~ ES-HAM-102) i hoʻomohala ʻia e SyncoZymes. Hiki i ka HAM ke hoʻoulu i ka ammoniation o ka waikawa enoic a i ʻole kāna mau derivatives e hana i nā waikawa amino chiral. Hiki ke hoʻohana ʻia ka HAM e synthesize i nā waikawa amino chiral (a i ʻole nā amino chiral) mai nā waikawa enoic (a i ʻole alkenes). Pono ka mea hāʻawi ammonia, e like me ka wai ammonia a i ʻole ka paʻakai ammonium.
ʻAno hana catalytic hydroaminase
Kelepona Paʻalima/Wechat/WhatsApp: +86-13681683526
Leka uila:lchen@syncozymes.com
-
CALB i hoʻopaʻa ʻia
KALB
Hoʻopuka ʻia ka Recombinant Lipase B mai Candida antarctica (CALB) ma o ka fermentation i lalo me ka Pichia pastoris i hoʻololi ʻia i ka genetically.
Hiki ke hoʻohana ʻia ʻo CALB i ka esterification catalytic phase wai a i ʻole ka organic phase, esterolysis, transesterification, ring opening polyester synthesis, aminolysis, hydrolysis of amides, acylation of amines a me ka hopena hoʻohui.
Loaʻa iā CALB ke koho chiral kiʻekiʻe a me ke koho kūlana, no laila hiki ke hoʻohana nui ʻia i ka hana ʻaila, ka meaʻai, nā lāʻau lapaʻau, nā mea hoʻonani a me nā ʻoihana kemika ʻē aʻe.
Kelepona Paʻalima/Wechat/WhatsApp: +86-13681683526
Leka uila:lchen@syncozymes.com
-
ʻO ka NADH oxidase (NOX)
E pili ana i ka NADH oxidase
ES-NOX (NADH oxidase): Hoʻoulu ka NOX i ka oxidation o NADH i NAD+, a no ka oxidoreductase. I ke kaʻina hana o ka oxidation, pono ʻo O2 ma ke ʻano he oxidant, a hoʻemi ʻia i H2O a i ʻole H2O2. Aia he 4 ʻano o nā huahana enzyme NOX (ES-NOX-101~ES-NOX-104) i hoʻomohala ʻia e kā mākou hui, hiki ke hoʻohana ʻia no ka hana hou ʻana o ka oxidation o ka coenzyme NAD+.
ʻAno hana catalytic:
or
Kelepona Paʻalima/Wechat/WhatsApp: +86-13681683526
Leka uila:lchen@syncozymes.com
-
ʻO ka lyase phenylalanine ammonia (PAL)
E pili ana i ka lyase ammonia Phenylalanine
ES-PAL: He papa o nā enzymes e hoʻoulu ai i ka deamination pololei o L-phenylalanine i ka waikawa trans-cinnamic. Ua hoʻomohala ʻo Syncozymes i 10 mau mea o ka phenylalanine ammonia lyase (i helu ʻia ʻo ES-PAL-101 ~ ES-PAL-110), hiki ke hoʻohana ʻia i ka deamination a i ʻole ka hopena hoʻohuli o ka phenylalanine a me kāna mau derivatives.
ʻAno hana catalytic:
Kelepona Paʻalima/Wechat/WhatsApp: +86-13681683526
Leka uila:lchen@syncozymes.com
-
ʻO Catalase (CAT)
E pili ana iā Catalase
ES-CAT (Catalase): hoʻoulu i ka hoʻoheheʻe ʻana o H2O2 i oxygen a me ka wai. Loaʻa nui ia i loko o ka mitochondria, endoplasmic reticulum, akepaʻa holoholona a me nā ʻulaʻula koko, ʻoi aku hoʻi i loko o ke akepaʻa ma ke kiʻekiʻe o ka hoʻohuihui ʻana, e hāʻawi ana i ka hana pale antioxidant no ke kino. I ka biocatalysis, hoʻohana nui ʻia ia e wehe i ka hopena hydrogen peroxide a hōʻemi i ka pale ʻana a me ka hoʻopau ʻana o ka enzyme e ka hydrogen peroxide. Hoʻokahi wale nō ʻano o nā huahana enzyme CAT i hoʻomohala ʻia e SyncoZymes (Helu e like me ES-CAT).
ʻAno hana catalytic:
Kelepona Paʻalima/Wechat/WhatsApp: +86-13681683526
Leka uila:lchen@syncozymes.com
-
Lysine oxidase (LO)
E pili ana iā Lysine oxidase
ES-LO (Lysine oxidase): hoʻoulu i ka oxidation o L-lysine i ka 6-amino-2-oxohexanoic acid (a i ʻole kona lactone). Hoʻokahi wale nō ʻano huahana enzyme LO (Helu e like me ES-LO) i hoʻomohala ʻia e SyncoZymes.
ʻAno hana catalytic:
Kelepona Paʻalima/Wechat/WhatsApp: +86-13681683526
Leka uila:lchen@syncozymes.com
